Quercetin: Managing Uric Acid with Quercetin Phytosome

Introduction

Elevated uric acid—hyperuricaemia—affects millions, contributing to gout, kidney stones and oxidative stress that impairs cellular health over time. By targeting the final enzyme in uric acid production, quercetin phytosome offers a botanical, well-tolerated approach to help maintain healthy uric acid levels and long-term vitality.

How Quercetin Phytosome Supports Uric Acid Balance

Quercetin, a plant-derived flavonoid, inhibits xanthine oxidase—the enzyme that converts xanthine into uric acid—thereby reducing its production and associated oxidative damage Tumova et al. 2021. However, standard quercetin suffers from poor solubility and low absorption, limiting its clinical utility.

Clinical Evidence for Uric Acid Reduction

In a randomised, double-blind, placebo-controlled trial, men who took 544 mg/day of quercetin phytosome for four weeks saw serum uric acid drop from 5.46 mg/dL to 5.04 mg/dL (p < 0.05) Di Pierro et al. 2025. This 7.7 % reduction not only underscores quercetin’s hypouricaemic effect but also highlights its potential as a safe adjunct in hyperuricaemia management without the side effects common to pharmaceutical XO inhibitors.

Enhancing Bioavailability through Phytosome Technology

Quercetin phytosome employs a lecithin-based delivery system that binds quercetin molecules to phospholipids, enhancing solubility and gastrointestinal uptake. A pharmacokinetic study demonstrated that this formulation increases oral absorption by over 20 -fold compared to unformulated quercetin Riva et al. 2019, enabling potent therapeutic effects at moderate dosages.

Synergy with NMN and Trans-Resveratrol for Metabolic Health

While quercetin phytosome helps control uric acid via XO inhibition, Nurix’s NMN supports cellular energy and DNA repair by boosting NAD⁺ levels Mills et al. 2016. Trans-Resveratrol activates sirtuin-1 (SIRT1), optimising metabolic flexibility and supporting healthy ageing pathways Baur & Sinclair 2006. Together, these compounds form a triad that addresses oxidative stress, inflammation and energy deficits—key factors in metabolic disorders and joint discomfort.

Incorporating Quercetin Phytosome into Your Routine

For adults aiming to manage uric acid levels, a daily dose of 544 mg quercetin phytosome (delivering ~200 mg pure quercetin) can be taken with meals to maximise absorption. As part of a balanced lifestyle—adequate hydration, reduced purine intake and regular exercise—this supplement helps maintain normal uric acid levels while supporting broader metabolic health.

Nurix’s vegan Quercetin Phytosome capsules are formulated to deliver this efficacious dose with clean, high-quality ingredients, free from gluten, dairy and artificial additives.

Conclusion

Quercetin phytosome represents a science-backed, botanical strategy to help manage hyperuricaemia naturally, offering significant uric acid reductions in just four weeks. When combined with NMN and Trans-Resveratrol, it forms a comprehensive approach to metabolic wellness, cellular resilience and long-term vitality.

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